Planta Med 2001; 67(6): 572-575
DOI: 10.1055/s-2001-16469
Letter

© Georg Thieme Verlag Stuttgart · New York

2-Substituted Furans from Polyalthia suberosa [1]

Patoomratana Tuchinda1,*, Manat Pohmakotr1 , Vichai Reutrakul1 , Wanpen Thanyachareon1 , Samaisukh Sophasan2 , Chalobon Yoosook3 , Thawatchai Santisuk4 , John M. Pezzuto5
  • 1 Department of Chemistry, Faculty of Science, Mahidol University, Bangkok, Thailand
  • 2 Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand
  • 3 Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand
  • 4 The Forest Herbarium, Royal Forestry Department, Bangkok, Thailand
  • 5 Program for Collaborative Reseach in the Pharmaceutical Science, College of Pharmacy, University of Illinois at Chicago, U.S.A.
Further Information

Publication History

August 10, 2000

September 2, 2000

Publication Date:
17 August 2001 (online)

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Abstract

Two new 2-substituted furans, 1-(2-furyl)pentacosa-16,18-diyne and 23-(2-furyl)tricosa-5,7-diynoic acid, have been isolated from stems of Polyalthia suberosa. The structures were assigned by spectroscopic methods. The two compounds together with the previously reported kalasinamide, N-trans-feruloyltyramine and N-trans-coumaroyltyramine showed anti-HIV activities.

1 1 Dedicated to the late Professor Leslie Crombie

References

1 1 Dedicated to the late Professor Leslie Crombie

Dr. Patoomratana Tuchinda

Department of Chemistry

Faculty of Science

Mahidol University

Bangkok 10400

Thailand

Email: scptc@mahidol.ac.th

Fax: +66-2-2477050

Phone: Tel.: +66-2-2458332